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龙哥查房——吴一龙教授肺癌典型病例分析及循证思维应用
$70.65
循证医学是近十余年来在临床医学实践中发展起来的一门新兴的临床学科,具体是指临床医生在获得患者准确的临床依据的前提下,根据自己的临床经验以及知识和技能,分析并找出患者主要的临床问题,应用、的科学证据对患者作出诊治决策。从临床研究到循证医学现实应用,广东省人民医院肺癌研究所团队一直是躬身力行的倡导者和实践者。本书是广东省肺癌研究所肺癌相关典型病例专家查房、病例讨论、循...
循证医学是近十余年来在临床医学实践中发展起来的一门新兴的临床学科,具体是指临床医生在获得患者准确的临床依据的前提下,根据自己的临床经验以及知识和技能,分析并找出患者主要的临床问题,应用、的科学证据对患者作出诊治决策。从临床研究到循证医学现实应用,广东省人民医院肺癌研究所团队一直是躬身力行的倡导者和实践者。本书是广东省肺癌研究所肺癌相关典型病例专家查房、病例讨论、循证诊疗精华,全书图文并茂,内容深入浅出,力求让临床肿瘤医生借鉴其中规范的循证医学诊疗思维模式,造福肿瘤患者。
本书展示了广东省肺癌研究所,定期于每周三下午举行的由吴一龙教授主持的,广东省肺癌研究所团队肺癌病例多学科大查房、大讨论,讨论形式从原始的广东省人民医院多学科专家共聚一堂、定期邀请国内专家参观交流和共同探讨,逐渐发展至目前国内网络直播、线上线下齐参与的“广东大会诊”。这些病例的讨论过程,均是医师们的心血及智慧的结晶。本书即为十几年来,广东省人民医院肺癌研究所肺癌相关典型病例的循证诊疗精华结集,主要内容包括MDT病例讨论、查房、循证思维报告等。
吴一龙,教授,博士生导师,IASLC杰出科学奖获得者,广东省人民医院首席专家,广东省肺癌研究所(GLCI)名誉所长,广东省肺癌转化医学重点实验室主任,吴阶平基金会肿瘤医学部会长,中国医师协会精准医学专委会副主任委员,广东省临床试验协会(GACT)会长,中国胸部肿瘤协作组(CTONG)主席,国际肺癌研究会(IASLC)理事会(BOD)核心成员,欧洲肿瘤学会(ESMO)中国区总代表。
部分
早中期肺癌篇
章 早期或复发结节鉴别
病例1 缓慢进展的肺部磨砂玻璃样结节的诊治 / 002
病例2 右上肺厚壁空洞并肺动脉栓塞后续治疗策略 / 011
病例3 系统性红斑狼疮合并肺结节的诊疗 / 018
病例4 高龄早期肺癌患者术后随访中肺部多发病灶的治疗 / 023
第二章 局部晚期肺癌多原发及寡转移的治疗策略
病例5 中央型鳞癌:新辅助化疗?辅助化疗? / 033
病例6 肺癌合并前列腺癌,如何兼顾治疗? / 038
病例7 肺癌合并鼻咽癌,如何兼顾治疗? / 049
病例8 双原发肺癌还是肺癌寡转移?辅助化疗还是辅助靶向治疗? / 057
病例9 合并鼻咽癌的双原发肺癌的治疗 / 066
第三章 局部进展肺癌放疗应用
病例10 Ⅲ期非小细胞肺癌的个体化治疗 / 075
病例11 EGFR/ALK阴性Ⅲ期肺癌,同步放化疗期间区分肿瘤进展和放疗反应是关键 / 085
病例12 新药临床试验异军突起的时代,如何把控标准治疗与尝试新药的界限? / 095
第四章 局部晚期非小细胞肺癌治疗中并发症的预防与管理
病例13 肺癌治疗过程中的乙肝病毒激活 / 102
病例14 ⅢA期中央型肺鳞癌伴发阻塞性肺炎:准确分期、控制感染后再行评估手术可行性和化疗方案选择 / 108
第五章 其他
病例15 ⅢA-N2肺癌克唑替尼新辅助治疗 / 115
病例16 pⅢA-N2肺腺癌R2切除后的治疗 / 128
病例17 EGFR的故事是否可复制:EML4-ALK融合的ⅢA-N2非小细胞肺癌患者的术后治疗选择 / 139
病例18 手术后超进展?EGFR突变肺腺癌局部治疗后快速进展 / 145
早中期肺癌病例篇章小结 / 151
第二部分
晚期肺癌篇
章 混合病理类型肺癌的治疗选择
病例19 复合型肺癌的诊治策略 / 154
病例20 EGFR 混合病理类型患者多线治疗后的选择 / 161
病例21 EGFR突变型肺腺癌混合大细胞神经内分泌癌,靶向治疗失败后出现病理转化及多基因突变,该如何分析? / 169
病例22 KIF5B-RET融合的肺腺鳞癌患者术后胸壁转移的治疗决策 / 179
第二章 EGFR治疗耐药后的治疗方案选择
病例23 一例EGFR突变晚期肺腺癌多线治疗后出现多个共存基因 / 184
病例24 一例EGFR-TKI原发耐药肺腺癌患者多线治疗后的方案选择 / 194
病例25 一例EGFR突变晚期肺腺癌伴脑膜及浆膜转移 / 202
病例26 多线靶向治疗后耐药的选择 / 210
病例27 Ⅳ期患者综合治疗后原发灶进展的治疗决策 / 216
病例28 缓慢进展型晚期非小细胞肺癌与时俱进的治疗策略——EGFR-TKI的使用及无治疗间期 / 222
第三章 其他
病例29 肺癌合并COPD出现气促加重,谁是罪魁祸首? / 233
病例30 罕见突变ROS1阳性肺癌综合治疗后的多发脑转移 / 240
晚期肺癌病例篇章小结 / 247
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