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胃癌综合诊治临床实践
$73.84
前沿的胃癌治疗,读这本就能了解!
胃癌是严重威胁我国人民生命与健康的重大疾病,近国内外针对胃癌不断涌现新的诊治方式和理念。本书编者是国内...
胃癌是严重威胁我国人民生命与健康的重大疾病,近国内外针对胃癌不断涌现新的诊治方式和理念。本书编者是国内知名医院的胃癌临床专家、学者和中青年骨干,代表了目前我国胃癌诊治的一线水平。本书的出版有益于规范和提高我国胃癌诊断与综合治疗的水平,是广大消化道肿瘤专科医师、研究人员及医学生的重要参考书籍。本书共十八章,全面介绍了胃癌的流行病学、发病机制、影像诊断、内镜诊断及其治疗、手术治疗、放射治疗、化疗、靶向治疗、免疫治疗及护理干预措施等方面的内容,特别强调了胃癌早发现、早诊断和综合诊治的重要性,并介绍了胃癌综合治疗领域近年来的新技术、新理念,包括生物技术、影像技术、AI技术在胃癌临床诊断中的应用与进展,胃癌创新外科手术、靶向治疗和免疫治疗的研究与临床实践等。
黄陈,上海交通大学附属人民医院胃肠外科主任,主任医师、博士生导师、博士后导师,上海交通大学医学院外科学博士、美国MD安德森癌症中心肿瘤学博士后、日本国立癌症中心访问学者。长期从事消化道肿瘤诊断与治疗,尤其在胃癌、结直肠癌微创外科治疗方面积累了丰富的临床经验,国内率先开展AI人眼追踪-4K高清-裸眼3D腹腔镜胃肠肿瘤手术、上海率先开展第四达芬奇机器人胃肠肿瘤手术、上海率先开展第四代达芬奇机器人单孔结直肠癌手术和胃肿瘤手术、国内率先开展第四代达芬奇机器人单孔"肠肝同切术",入选平安中国好医生榜上海胃肠外科医师。完成人分别获得上海市医学科技奖青年奖、上海市抗癌科技奖二等奖、上海市优秀发明选拔赛优秀创新奖银奖。长期从事胃肠肿瘤基础研究、转化研究和临床研究。主持国家自然科学基金四项,上海市科委、上海市卫健委等课题多项。申请实用新型专利三项、发明专利一项。在Cancer Research、Clinical Cancer Research等SCI期刊发表或通讯作者论文四十余篇。
章 胃癌流行病学和检查诊断………………………………………… 1节 胃癌流行病学……………………………………………………… 1第二节 胃癌风险因素分析………………………………………………… 3第三节 胃癌检查与诊断…………………………………………………… 3第二章 胃癌预防、筛查、诊治流程和分期………………………………… 7节 胃癌预防…………………………………………………………… 7第二节 胃癌筛查…………………………………………………………… 7第三节 胃癌诊治流程……………………………………………………… 9第四节 胃癌分期………………………………………………………… 12第三章 胃癌预后预测模型建立和发展………………………………… 20节 Cox回归分析的胃癌预后预测模型…………………………… 20第二节 Nomogram模型………………………………………………… 21第三节 神经网络模型…………………………………………………… 23第四节 深度学习模型…………………………………………………… 23第五节 其他预后预测模型……………………………………………… 24第六节 总结和展望……………………………………………………… 25第四章 病理特征在胃癌新型分期探索与思考………………………… 27节 肿瘤间质成分在胃癌微环境中的联系与作用………………… 28第二节 病理特征在胃癌分期和预后评判中的价值…………………… 31第五章 胃癌发生发展分子机制………………………………………… 33节 胃癌发生发展分子机制………………………………………… 33第二节 miRNAs与胃癌发生发展……………………………………… 42第三节 lncRNA与胃癌发生发展……………………………………… 45第四节 环状RNA与胃癌发生发展…………………………………… 48 2 胃癌综合诊治临床实践第五节 Hp感染、萎缩性胃炎与胃癌…………………………………… 52第六章 近、远端胃癌差异………………………………………………… 56节 远、近端胃癌流行病学差异……………………………………… 57第二节 远、近端胃癌病因学和细胞来源差异…………………………… 58第三节 远、近端胃癌病理学特征差异…………………………………… 60第四节 远、近端胃癌临床表现差异……………………………………… 67第五节 远、近端胃癌手术治疗及预后差异……………………………… 67第六节 远、近端胃癌预防差异…………………………………………… 69第七章 肿瘤标志物犆犃72 4与胃癌…………………………………… 71节 CA72 4简介…………………………………………………… 71第二节 CA72 4作为胃癌生物标志物………………………………… 71第三节 CA72 4作为胃癌预测因子…………………………………… 75第四节 CA72 4作为胃癌治疗靶点…………………………………… 76第五节 其他肿瘤标志物与胃癌………………………………………… 77第八章 超声技术在胃癌中应用………………………………………… 78节 超声技术在胃癌中的应用概述………………………………… 78第二节 胃癌超声典型影像表现………………………………………… 82第三节 超声技术在胃癌诊断和治疗中的应用………………………… 92第九章 影像学在胃癌中的应用………………………………………… 98节 胃癌影像学诊断概述…………………………………………… 98第二节 胃癌影像学检查方法…………………………………………… 98第三节 胃癌影像学表现………………………………………………… 100第十章 18犉犉犇犌犘犈犜/犆犜显像在胃癌诊治中的应用……………… 111节 18F FDGPET/CT显像原理及在胃癌中的应用概述……… 111……
胃癌是常见的恶性肿瘤之一,严重威胁着人类的生命与健康。我国是胃癌高发国家,根据我国的癌症统计数据显示,胃癌的发病率与死亡率在所有恶性肿瘤中均位居第3位,且我国胃癌的发病人数与死亡人数将近全球一半,因此降低胃癌的发病率与死亡率是亟待解决的重大公共卫生问题。近年来随着医学的发展,胃癌的治疗模式逐渐由传统的单纯肿瘤根治性切除转换为以肿瘤根治性切除为主的多学科综合诊疗模式,该模式下不仅要求有精湛的手术技能,还需要诸如消化内镜诊断、影像学评估、病理学评估、分子分型基因检测以及围手术期放化疗等多种诊疗手段共同参与。在这种综合诊疗模式的快速发展过程中,国内外针对胃癌不断涌现新的诊治方式和理念。目前国内外关于胃癌综合诊治的专著较少,多数以手术图谱为主的胃癌外科手术介绍或者以化疗方案为主的胃癌内科治疗介绍。为从更加全面的视角介绍当前胃癌综合治疗领域的创新思想与前沿技术,本书总结了国内外的研究现状,在介绍的胃癌发生、发展机制基础上,围绕胃癌诊断、治疗方面的新技术与的转化研究进行详细阐述,力求使读者以更广泛的视野了解胃癌综合领域的前沿进展,旨在促进胃癌相关研究开展、普及胃癌新型诊疗技术、推广胃癌综合诊治理念。本书从流行病学入手开启对胃癌的直观认识,内容覆盖从胃癌的发生发展机制到胃癌的诊断与治疗,从阶段性治疗到全周期治疗与管理,从单一专科到多学科共同参与,力求为胃癌综合诊治研究领域注入新思考与新力量。然医学求知路漫漫,因我们时间与学识有限,本书中难免有不足之处,敬请各位同仁与广大读者批评指正,不吝赐教。
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