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糖尿病及肥胖诊治新技术
$60.08
1. 作者权威:贾伟平,2021年当选为中国工程院院士,长期致力于糖尿病精准诊疗、预警筛查、发病机制的研究及防治工程管理。现任上海交通大学医学院附属第六人民医院教授、主任医师,国家基层糖尿病防治管理办公室主任,上海市糖尿病临床医学中心主任,上海市糖尿病重点实验室主任,上海市糖尿病研究所所长,上海市政府参事。2. 前沿技术:本书对糖尿病及肥胖症的临床新技术和新成果进行了系统阐述,介绍了糖尿病病理生理评估新技术、糖尿病...
1. 作者权威:贾伟平,2021年当选为中国工程院院士,长期致力于糖尿病精准诊疗、预警筛查、发病机制的研究及防治工程管理。现任上海交通大学医学院附属第六人民医院教授、主任医师,国家基层糖尿病防治管理办公室主任,上海市糖尿病临床医学中心主任,上海市糖尿病重点实验室主任,上海市糖尿病研究所所长,上海市政府参事。2. 前沿技术:本书对糖尿病及肥胖症的临床新技术和新成果进行了系统阐述,介绍了糖尿病病理生理评估新技术、糖尿病精确诊断和监测新技术、肥胖症测定新技术、多学科协作下的代谢/减重治疗手术、代谢性疾病的防控新技术及2型糖尿病风险及降糖药物疗效的遗传预测技术等。3. 读者对象:从事内分泌代谢性疾病临床、教学及科研工作的临床医生和研究人员。
本书对糖尿病及肥胖症的临床新技术和新成果进行了系统阐述,介绍了糖尿病病理生理评估新技术、糖尿病精确诊断和监测新技术、肥胖症测定新技术、多学科协作下的代谢/减重治疗手术、代谢性疾病的防控新技术及2型糖尿病风险及降糖药物疗效的遗传预测技术等,有助于糖尿病及肥胖症的早期筛查、明确诊断、快速鉴别、及时评估及个体化治疗。 本书可作为从事内分泌代谢性疾病临床、教学及科研工作的临床医生和研究人员的参考书,亦可供医学院校相关专业医学生、研究生和内科住院医师在临床工作中使用。
贾伟平,中国工程院院士,博士生导师,上海交通大学医学院附属第六人民医院教授、主任医师,国家基层糖尿病防治管理办公室主任,上海市糖尿病临床医学中心主任,上海市糖尿病重点实验室主任,上海市糖尿病研究所所长,上海市政府参事。长期从事糖尿病防治领域的临床、科研及工程管理工作。以、二完成人分别获得国家科学技术进步奖二等奖2项,以完成人获得省部级科学技术进步奖一等奖5项。以通信或共同通信作者在Nature子刊、Lancet子刊、BMJ及Diabetes等期刊发表SCI论文299篇,连续七年入选Elsevier全球高被引学者榜单。主编学术专著7部,其中英文专著1部。2011年任国家重点基础研究发展计划(973计划)首席科学家,2015年获吴阶平-保罗•杨森医学药学奖,2016年获何梁何利基金科学与技术进步奖,2017年获亚洲糖尿病流行病学杰出研究奖,2019年获谈家桢生命科学临床医学奖,2020年当选中国医学科学院学部委员。荣获全国三八红旗手、全国优秀科技工作者、全国先进工作者等称号。当选第十一、十二届全国人大代表。
章 糖尿病病理生理评估新技术001节 评估胰岛素敏感性的“金标准”:高胰岛素 正葡萄糖钳夹技术·005第二节 精确评估胰岛 β 细胞功能的“金标准”:高葡萄糖钳夹技术·015第三节 精确评估胰岛 β 细胞分泌功能早期变化新技术:胰岛素慢速脉冲分泌波动检测技术·022第四节 临床常用的胰岛 β 细胞分泌功能评估方法:葡萄糖耐量 胰岛素释放试验·047第五节 衡量胰岛 β 细胞储备功能的非糖物质刺激试验·056第二章 糖尿病诊断和监测新技术067节 糖尿病个体化治疗的精密监测技术:持续葡萄糖监测·068第二节 糖尿病诊断及控制评估指标:糖化血红蛋白·082第三节 糖尿病控制评估指标:糖化白蛋白·095第三章 肥胖症测定新技术109节 肥胖的测定方法和诊断标准·110第二节 精确测定人体腹部体脂分布的磁共振法·116第三节 适用于人群腹型肥胖诊断的简易参数·124第四节 静息能量消耗的间接测热技术·133第四章 多学科协作下的代谢/ 减重手术137第五章 代谢性疾病的防控新技术149节 中国糖尿病和肥胖病的防控现状·150第二节 慢性非传染性疾病防控理念·156第三节 代谢性疾病的一线防控:“守门人”角色·159第四节 人工智能技术助力糖尿病并发症筛查·181第五节 代谢性疾病防控的三级联动模式·187第六章 2 型糖尿病风险及降糖药物疗效的遗传预测技术195节 2 型糖尿病的遗传预警技术·196第二节 降糖药物疗效的遗传预测技术·209
过去的30年里,我国经济飞速发展,人们的生活方式、饮食习惯都发生了巨大变化,同时也伴随着疾病谱的改变,以糖尿病为代表的各种慢性疾病死亡数已占到了全部死亡人数的88.5%。《中国统计年鉴2021》报道我国总人口为14.1212亿,其中34.3%的人超重,16.4%肥胖;11.9%的成人患有糖尿病。糖尿病导致的多种并发症和合并症,如失明、肾功能衰竭、截肢、心肌梗死、卒中已成为人类致死和致残的主要病因,这不仅对患者身心健康造成巨大损害,亦对我国医疗卫生体系的慢病防控提出了严峻挑战。应对糖尿病的防控策略是关口前移,加速遏制,逐渐消除糖尿病对实际人群的健康危害。根据糖尿病发生和发展的临床进程,设置了降低糖尿病发病率、提高知晓率和血糖控制率、降低慢性并发症与合并症发病率、降低重要器官功能衰竭发生率、降低伤残率和病死率等各阶段目标。当前,在我国进入全面建设社会主义现代化国家新时代的关键时期,国家更是把保障人民健康放在优先发展战略位置。深入开展健康中国行动,坚持预防为主,加强重大慢性病的健康管理。为了更好地担负起“坚持面向人民生命健康”历史赋予的重任,不断探索疾病的发病机制,创新预防及诊疗的技术,及时开展培训和推广,使得更多的专业工作者和民众获益——这正是本书所有编者的初心和践行使命的具体举措。上海交通大学医学院附属第六人民医院内分泌代谢科成立30余年来,聚焦糖尿病、肥胖等重大代谢性疾病,开展病因、发病机制、早期筛查、精准诊治、监测管理等研究和新技术的开发,取得了一系列的科研成果,在国内外都产生了较大影响力。本书内容汇总了各位编者多年的科研工作成果及国内外研究进展。在糖尿病方面,分别介绍了精确评估糖尿病病理生理的技术和科研或临床适用的方法,包括糖尿病精准诊治新技术、基层适用技术及管理方案,持续葡萄糖监测的关键技术、临床应用的标准及发展前景,以及糖尿病遗传和环境风险预警技术的建立与应用等。在肥胖症方面,着重揭示中国肥胖症的临床特点,介绍精密测定技术和简易测量方法的建立及临床应用,尤其是编者团队创立的多学科团队协作下的代谢减重手术的系列研究成果。还值得一提的是,编者在长期积累的临床诊治经验和社区防控实践的基础上,结合对我国代谢性疾病实际防控情况的评估,充分考虑地区文化、社会经济和制度等方面的差异性,创建适合中国人群的代谢性疾病防控模式.希望本书的出版能为我国糖尿病和肥胖症的预防和干预提供新的研究思路和技术方法,促进新技术向临床应用转化,进一步提升、优化我国糖尿病和肥胖症的综合管理体系,并在指导临床医生开展临床和科研工作、科普代谢性疾病相关核心知识及教育医学院校学生等多方面,能有所助益。
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