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喉癌:临床病例精要
$60.98
该书原著集聚了诸多来自世界各国的耳鼻咽喉—头颈外科、放 / 化疗科和影像科等各学科专家,共同编写了这一具有划时代意义的专业图书。该书从喉癌病例着手,深入浅出地阐述了喉癌的发病、诊断、治疗方案、围手术期处理、注意事项及如何避免误区,内容翔实,图片精美。
本书由国际著名耳鼻咽喉—头颈外科、放 / 化疗科和影像科等学科专家 Rogério A. Dedivitis, Giorgio Peretti,Ehab Hanna, Claudio R. Cernea 等共同编写,是一本具有划时代意义的专业图书。本书基于喉癌病例报道的形式,汇集了典型病例,融入了当代喉癌诊治代表性与国际化的新理念,为喉癌诊治提供了新的策略。全书共 34 个专题,每个专题包含病例介绍、讨论、建议和避免误区等部分,并配以精美的图片与表格,通过翔实的病例,深入浅出地分析了临床术式选择依据、影像学检查结果、手术技巧、手术并发症及其处理方法等,针对临床常见的各种类型的喉癌,从诊断、治疗及预后进行了详细剖析。本书实用性强,可供各年资的耳鼻咽喉—头颈外科、放 /化疗科、影像科及相关专业医师和医学生借鉴阅读,也有助于促进我国在该领域的基础和临床研究,进一步提高相关专业医师的临床诊断和治疗水平。
Rogério A. Dedivitis [巴西],圣保罗大学医学院头颈外科教授,博士。Giorgio Peretti[意],热那亚大学头颈外科主任,教授。Ehab Hanna[美], 德克萨斯大学安德森癌症中心头颈外科教授,副主席。Claudio R. Cernea[巴西], 圣保罗大学医学院头颈外科教授助理。
1 T1a期的声门型喉癌经口激光手术 1
T1a Glottic Carcinoma Undergoing Transoral Laser Surgery
1.1 病例介绍 1
1.2 讨论 2
1.3 建议 3
1.4 避免误区 3
2 T1a期声门癌的放射治疗 5 Radiotherapy for T1a Glottic Cancer
2.1 病例介绍 5
2.2 讨 论 6
3 早期喉癌的机器人手术治疗 10
Robotic Surgery for Early-Stage Laryngeal Cancer
3.1 病例介绍 10
3.2 讨论 12
3.3 建议 12
3.4 避免误区 12
4 经口入路激光手术治疗T1b声门癌 14 T1b Glottic Cancer Treated with Transoral Laser Surgery
4.1 病例介绍 14
4.2 讨论 15
4.3 建议 17
4.4 避免误区 17
5 T1b声门型喉癌 19
T1b Glottic Cancer
5.1 前言 19
5.2 评估 19
5.3 治疗方案选择 20
5.4 发音质量 20
5.5 模拟定位和治疗计划 21
5.6 分割 21
5.7 远期因素和继发性恶性肿瘤 22
5.8 戒烟 22
6 T1b声门型喉癌和垂直部分喉切除术 24
T1b Glottic Cancer, Vertical Partial Laryngectomy
6.1 病例介绍 24
6.2 讨论 25
6.3 建议 27
6.4 避免误区 27
7 声门上型喉癌的经口激光显微手术 29
Transoral Laser Microsurgery for Intermediate Supraglottic Cancer
7.1 病例介绍 29
7.2 讨论 31
7.3 建议 32
7.4 避免误区 32
8 放疗在早期声门上型喉癌治疗中的作用 33
The Role of Radiation Therapy in Early-Stage Supraglottic Cancer
8.1 病例介绍 33
8.2 讨论 35
8.3 建议 37
8.4 避免误区 37
9 早期声门上型喉癌:声门上水平部分喉切除术 39
Early Supraglottic Cancer: Horizontal Supraglottic Laryngectomy
9.1 病例介绍 39
9.2 讨论 40
9.3 建议 42
9.4 避免误区 42
10 局部中期声门癌:经口激光显微手术 43
Locally Intermediate Glottic Cancer: Transoral Laser Microsurgery
10.1 病例介绍 43
10.2 讨论 45
10.3 建议 46
10.4 避免误区 46
11 局部中期声门癌:放化疗 48
Locally Intermediate Glottic Cancer: Chemoradiotherapy
11.1 病例介绍 48
11.2 讨论 49
11.3 建议 51
11.4 避免误区 52
12 局部中期声门型喉癌:垂直部分喉切除术 54
Locally Intermediate Glottic Cancer: Vertical Partial Laryngectomy
12.1 病例介绍 54
12.2 讨论 55
12.3 建议 56
12.4 避免误区 57
13 局部中期声门癌:喉环状软骨上切除—环舌会厌吻合术 58
Locally Intermediate Glottic Cancer: Supracricoid Laryngectomy with CHEP
13.1 病例介绍 58
13.2 讨论 59
13.3 建议和避免误区 60
14 经口机器人手术治疗晚期喉癌 62
Transoral Robotic Surgery for Advanced Laryngeal Cancer
14.1 病例介绍 62
14.2 治疗方案示意图(TORS结合诱导化疗) 62
14.3 治疗方案适应证 63
14.4 诱导化疗方案 63
14.5 手术过程 63
14.6 辅助治疗 65
14.7 治疗结果 65
14.8 思考 66
15 局部晚期声门上型喉癌:通过经口激光显微外科手术保留喉 69
Locally Advanced Supraglottic Cancer: Larynx Preservation by Transoral Laser Microsurgery
15.1 病例介绍 69
15.2 讨论 70
15.3 结论 72
15.4 建议 72
15.5 避免误区 73
16 局部中期声门上区癌:放射治疗 75
Locally Intermediate Supraglottic Cancer: Radiotherapy
16.1 病例介绍 75
16.2 讨论 77
16.3 建议 78
16.4 避免误区 78
17 局部中期声门上型喉癌:环状软骨上喉部分切除及环舌骨吻合术 80
Locally Intermediate Supraglottic Cancer: Supracricoid Laryngectomy with Cricohyoidopexy
17.1 病例介绍 80
17.2 讨论 81
17.3 建议 82
17.4 避免误区 82
18 局部晚期声门型喉癌:环状软骨上喉部分切除术 84
Locally Advanced Glottic Cancer: Supracricoid Laryngectomy
18.1 病例介绍 84
18.2 讨论 86
18.3 建议 87
18.4 避免误区 87
19 喉垂直部分切除及气管自体移植术 89
Hemicricolaryngectomy with Tracheal Autotransplantation
19.1 病例介绍 89
19.2 讨论 91
19.3 建议 93
19.4 避免误区 93
20 局部晚期声门型喉癌:气管上喉部分切除术 96
Locally Advanced Glottic Cancer: Supratracheal Laryngectomy
20.1 临床病例1 96
20.2 临床病例2 97
20.3 讨论 98
20.4 建议 99
20.5 避免误区 100
21 局部晚期声门型喉癌:喉全切除术与发音假体应用 102
Locally Advanced Glottic Cancer: Total Laryngectomy and Voice Prostheses
21.1 病例介绍 102
21.2 讨论 105
21.3 建议 106
21.4 避免误区 106
22 经口入路机器人辅助喉全切除术:按步手术技术 107
Transoral Robotic Surgical Total Laryngectomy: The Technique Step by Step
22.1 简介 107
22.2 病例和手术方法 107
22.3 讨论 111
22.4 结论 111
23 局部晚期声门上型喉癌:保喉策略 113
Locally Advanced Supraglottic Cancer: Organ-Preservation Protocol
23.1 病例介绍 113
23.2 讨论 114
24 首次放疗后的挽救性手术:经口激光显微手术 116
Salvage Surgery after Primary Radiotherapy: Transoral Laser Microsurgery
24.1 病例介绍 116
24.2 讨论 117
24.3 建议 118
24.4 避免误区 118
25 放疗后挽救性手术:环状软骨上喉部分切除术 120
Salvage Surgery after Radiotherapy: Supracricoid Laryngectomy
25.1 病例介绍 120
25.2 讨论 121
25.3 建议 122
25.4 避免误区 122
26 放疗后挽救性手术:喉全切除术 124
Salvage Surgery after Radiotherapy: Total Laryngectomy
26.1 病例介绍 124
26.2 外科操作 125
26.3 讨论 126
26.4 建议 127
26.5 避免误区 127
27 避免咽瘘的策略:胸大肌皮瓣在挽救性喉全切除术中的应用 129
Strategy for Avoiding Pharyngocutaneous Fistula: Pectoralis Muscle Flap for Salvage Total Laryngectomy
27.1 病例介绍 129
27.2 讨论 131
27.3 建议 133
27.4 避免误区 133
28 晚期喉癌重建:胸大肌肌皮瓣 135
Reconstruction for Advanced Cancer: Pectoralis Major Myocutaneous Flap
28.1 简介 135
28.2 外科技术 135
28.3 晚期喉癌治疗的主要适应证 135
28.4 并发症 136
28.5 功能性结果 136
28.6 临床病例 136
29 晚期喉癌重建:锁骨上岛状皮瓣 139
Reconstruction for Advanced Cancer: Supraclavicular Island Flap
29.1 病例介绍 139
29.2 讨论 139
29.3 建议 142
29.4 避免误区 142
30 晚期喉癌重建:背阔肌肌皮瓣 144
Reconstruction for Advanced Cancer: Latissimus Dorsi Myocutaneous Flap
30.1 病例介绍 144
30.2 讨论 146
30.3 建议 147
30.4 避免误区 147
31 胃上提 148
Gastric Pull-Up
31.1 历史 148
31.2 适应证 149
31.3 禁忌证 149
31.4 术前准备 149
31.5 手术步骤 149
31.6 并发症 152
32 早期原发性肿瘤伴晚期颈部疾病 154
Early Primary Tumor with Advanced Neck Disease
32.1 简介 154
32.2 临床病例 154
32.3 检查结果 155
32.4 治疗方案 156
32.5 手术后直接辅助治疗 156
32.6 同步放化疗 156
32.7 化疗选择 156
32.8 挽救性颈淋巴结清扫术 157
32.9 病例总结 157
33 靶向药物治疗晚期喉鳞状细胞癌 159
Targeted Therapy for the Treatment of Advanced Squamous Cell Carcinoma of the Larynx
33.1 导言 159
33.2 案例讨论 159
33.3 一线治疗中抗表皮生长因子受体肿瘤靶向治疗 159
33.4 病例讨论(续) 160
33.5 铂类化疗失败后的靶向治疗 160
33.6 预测生物标志物 162
33.7 未来方向 162
34 喉移植 165
Laryngeal Transplantation
34.1 病例介绍 165
34.2 讨论 166
34.3 建议 167
34.4 避免误区 167
索引 168
喉居于颈前正中,上达喉咽,下通气管,后毗邻食管。喉具有呼吸、发声、吞咽和保护等功能,故喉部疾病轻者影响发声与呼吸,重者甚至可危及生命。喉癌是头颈部常见的恶性肿瘤,占头颈恶性肿瘤的25%,其精准的诊断与治疗方案选择与喉癌患者的生存率及生存质量休戚相关,目前仍是耳鼻咽喉—头颈肿瘤外科领域一大难题。有鉴于此,我们翻译了Laryngeal Cancer: Clinical Case-Based Approaches一书。
本书原著聚集了来自世界各国的耳鼻咽喉—头颈外科、放/化疗科和影像科等各学科专家,共同编写了这一具有划时代意义的专业图书。该书从喉癌病例着手,深入浅出地阐述了喉癌的发病、诊断、治疗方案、围手术期处理、注意事项及如何避免误区,内容翔实,图片精美。作为耳鼻咽喉—头颈外科临床医师,我们深感自己所肩负的责任与义务,故组织了本学科优秀专业骨干翻译本书。在翻译过程中,我们深切体会到本书原著编者高超的临床智慧和严谨的科学态度。
虽然本书译者进行了仔细翻译并相互校对,主译也进行了仔细校对,但受水平所限,难免有不当及疏漏之处,敬请读者批评指正。在本书出版之际,我们衷心感谢宁波市卫生健康委员会和宁波市医疗中心李惠利医院领导的大力支持,感谢各位译者的辛勤付出,同时感谢家人的支持与鼓励!
沈志森 沈 毅2021年6月于宁波市医疗中心李惠利医院
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