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儿童血液系统疾病诊疗规范 (第2版/配增值)
$51.89
★ “儿科疾病诊疗规范”丛书是“十三五”国家重点出版物出版规划项目,由中华医学会儿科学分会组织编写,第1版于2014年始陆续出版,各分册深受读者欢迎。其出版推动了儿科临床诊治的规范化,满足了广大儿科临床工作者的需求。 ★ 第2版“儿科疾病诊疗规范”丛书仍由中华医学会儿科学分会组织编写,丛书总主编为桂永浩教授和王天有教授,各分册主编均由各学组组长担任,组织学组内有丰富临床经验的专家共同编写,力求为广大儿科医生提供一套真正可信、可读、可用、可行的行业诊治规范。 ★ 本套丛书共18个分册,内容包含各位专家多年总结的临床经验,并有科学的评价证据支持,以循证医学为基础,将规范化医疗与个体化医疗相结合。针对每种具体疾病,按照“概述、诊断、鉴别诊断、治疗”清晰阐释,并附有诊治流程图,简洁实用、可读性强。★ 采用融合出版的形式,各分册附赠精彩儿科诊治临床实操视频,可扫码观看,全面提升读者阅读体验。★ 可作为卫生主管部门组织的培训课程的教材,成为岗位胜任能力培训的重要内容。本套丛书正在陆续出版中,谨此献给所有的儿科医师!
新版承袭版特点,修订幅度在30%以上,重点讲述各种血液病和肿瘤的诊断的治疗,如小儿贫血、骨髓衰竭性疾病、出凝血疾病、血液肿瘤性疾病、骨髓增值性疾病、组织细胞性疾病、以及造血干细胞移植的应用等,并附有大量诊治流程图,为读者提供分析思路。内容系统完整,结构严密,科学准确,可读性强,合适的图表、诊治流程图,能帮助儿科医务工作者快速诊断病情。
吴敏媛:中华医学会儿科学分会血液学组组长、顾问,国家卫生健康委儿童白血病专家委员会顾问,中国女医师协会儿科专业委员会委员。王天有:中华医学会儿科学分会主任委员,中国医师协会儿科医师分会副主任委员,中国医疗保健国际交流促进会儿科学分会主任委员。刘玉峰:中国小儿血液研究专家委员会委员、河南省抗癌学会儿科专业委员会副主委。
章 | 贫血 / 1节 总论/1第二节 营养性缺铁性贫血/ 7第三节 营养性巨幼细胞贫血/15| 第二章 | 溶血性贫血/22节 总论/22第二节 地中海贫血/27第三节 红细胞葡萄糖 -6- 磷酸脱氢酶缺乏症/35第四节 遗传性球形红细胞增多症 / 39第五节 自身免疫性溶血性贫血 / 43第六节 溶血危象 / 49| 第三章 | 骨髓衰竭性疾病/54节 总论/54第二节 获得性再生障碍性贫血 / 59第三节 范科尼贫血/66第四节 先天性纯红细胞再生障碍性贫血 / 75第五节 先天性中性粒细胞减少症 / 80第六节 先天性血小板减少症/89| 第四章 | 出凝血疾病/98节 总论/98第二节 原发性免疫性血小板减少症/102第三节 血友病 / 109第四节 获得性凝血因子缺乏性疾病/115第五节 静脉血栓栓塞症 / 130| 第五章 | 恶性血液肿瘤性疾病/140节 总论/140第二节 急性淋巴细胞白血病/147第三节 复发急性淋巴细胞白血病 / 167第四节 急性髓系白血病 / 179第五节 非霍奇金淋巴瘤 / 194第六节 霍奇金淋巴瘤/213第七节 神经母细胞瘤/219第八节 视网膜母细胞瘤 / 227第九节 肾母细胞瘤/232第十节 肝母细胞瘤/241第十一节 横纹肌肉瘤/255第十二节 常用抗肿瘤药物/ 260| 第六章 | 骨髓增殖性疾病 / 骨髓增生异常综合征 /.311节 总论/311第二节 真性红细胞增多症/ 313第三节 原发性血小板增多症/320第四节 嗜酸性粒细胞疾病/ 324第五节 慢性髓细胞性白血病/333第六节 幼年型粒 - 单核细胞白血病 / 340第七节 骨髓增生异常综合征/346| 第七章 | 组织细胞疾病 / 357节 总论/357第二节 噬血细胞性淋巴组织细胞增生症 / 360第三节 朗格汉斯细胞组织细胞增生症/372| 第八章 | 主要血液系统罕见病/383节 总论/383第二节 重症联合免疫缺陷病/386第三节 慢性肉芽肿病/390第四节 极早发型炎症性肠病/393第五节 戈谢病 / 400第六节 尼曼 - 皮克病/406第七节 慢性活动性EB 病毒感染/412| 第九章 | 造血干细胞移植的应用 / 424节 总论/424第二节 恶性疾病造血干细胞移植适应证 / 425第三节 非恶性疾病造血干细胞移植适应证 /434第四节 移植并发症处理 / 445| 第十章 | 血液肿瘤常见并发症处理/466节 肿瘤溶解综合征 / 466第二节 肿瘤相关性上腔静脉综合征/469第三节 化疗药物相关重症合并症 / 473第四节 中性粒细胞缺乏伴发热处理原则 / 483第五节 抗细菌治疗/488第六节 抗真菌治疗/493第七节 抗病毒治疗/499第八节 血液成分的临床应用/507第九节 造血生长因子的临床应用 / 515(以下视频需下载“人卫图书增值客户端”,扫描方法见目录前说明)视频 儿童骨髓穿刺术 / 333
随着我国经济发展和人民生活水平的迅速提升,人群疾病谱发生了很大变化。过去常见的一些儿科血液系统疾病的发病率不断降低,而白血病及其他恶性肿瘤对儿童健康造成的威胁则日益显著,恶性肿瘤已成为儿童期死亡的主要原因之一。面对这些变化,我国儿科血液病工作者及时调整专业重心,将恶性血液病的诊断、治疗放在了突出的位置,不断吸收、消化并改进国外先进诊疗技术与理念,始终如一地强调科学性、严谨性,开展了许多新的工作,积累了宝贵的经验,在儿科血液病的规范化诊疗方面取得了长足的进步。例如,开展规范的MICM 分型,特别是分子生物学分型;准确检测早期治疗反应,优化危险度评估,从而实施精准的分层治疗;不断将手术、化疗与放疗等基本治疗手段优化组合,广泛应用造血干细胞移植、免疫治疗、细胞治疗、分子靶向治疗等新技术、新方法,极大地减少了疾病的复发;支持治疗的熟练应用也使化疗的安全性得到很大提高;在不断提高患儿的无病生存率的同时,更加关注并提升长期生存患儿的生活质量。通过这些努力,儿童恶性血液病的疗效得到极大提高,急性淋巴细胞白血病和淋巴瘤的长期无病生存率已达到80% 以上,实体瘤也提高到60%~70%。与此同时,儿科血液病学界并没有忽视非恶性血液病的临床及科研工作,规范了常见血液疾病的诊治;更新了免疫性血小板减少性紫癜的治疗理念;对血友病患儿进行次级预防,减少致残率;对地中海贫血患儿根据年龄、铁负荷和累及器官程度进行分层评估及选择治疗,重型患儿采用造血干细胞移植治疗。近年来,随着基因检测技术如高通量测序的临床应用,儿科遗传性和罕见血液病,如遗传性骨髓衰竭性疾病、溶酶体贮积症、过氧化物酶体病以及线粒体病等遗传代谢病、原发性免疫缺陷病等,都在早诊断、早治疗方面取得了长足的进步,并且在某些疾病开展了具有儿科特色的小年龄造血干细胞移植。所有这些工作都已成为儿科血液病领域的亮点。撰写本书的目的就是将这些宝贵的经验向广大儿科血液病工作者,特别是具有中、高级职称者进行推广。为使读者能够读得明白,用得方便,特别绘制了诊疗流程图,提出了贫血、出血、溶血等疾病的分析思路。因此,本书将对规范临床诊疗行为,提高我国儿科血液病的临床服务质量和整体治疗水平、降低诊疗费用起到积极的促进作用。在编写中,各位编者、审稿专家付出了大量的心血,在此表示衷心的感谢!本书出版之际,恳切希望广大读者在阅读过程中不吝赐教,欢迎发送邮件至邮箱renweifuer@pmph.com,或扫描封底二维码,关注“人卫儿科学”,对我们的工作予以批评指正,以期再版修订时进一步完善,更好地为大家服务。吴敏媛 王天有 刘玉峰2023 年3 月
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