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临床研究基本概念(第2版)
$49.57
1.首版中文版深受读者欢迎销量过万,好评如潮。豆瓣评分9.2/10。读者评论:“简单粗暴有观点”“通俗易懂”“言简意赅”“科学实用”“临床研究红宝书”……
2.独辟蹊径,颠覆传统讲解案例丰富,既有国际上知名的研究案例,也夹杂来自日常生活的实例。语言轻松诙谐,深入浅出,清晰讲解临床研究中的基本概念和试验设计思路。不仅涵盖基本观点、基本概念,也对临床研究学...
2.独辟蹊径,颠覆传统讲解案例丰富,既有国际上知名的研究案例,也夹杂来自日常生活的实例。语言轻松诙谐,深入浅出,清晰讲解临床研究中的基本概念和试验设计思路。不仅涵盖基本观点、基本概念,也对临床研究学领域尚存的争论进行了探讨。
3.第2版内容更为翔实,实用性更强第1版中文版20万字,第2版34万字,内容更为全面丰富。第2版对原有的16章进行了深入修订,并增加了全新6章,均为临床研究中非常重要的主题。同时,更新参考文献。
4.译者团队专业权威中文版出自我国循证医学发源地之一的复旦大学循证医学中心,由我国著名临床医学家、循证医学的领头人王吉耀教授领衔翻译,为读者奉上原汁原味的作品。
5.装帧升级,全彩印刷,延续小手册设计相较于第1版黑白版式、胶版纸印刷,第2版全书升级为全彩版式、铜版纸印刷,以提供*为优质的阅读效果。延续中文版第1版小开本的设计,方便读者随时随地携带和翻阅。
《临床研究基本概念》内容涵盖随机对照试验、描述性研究、队列研究、病例-对照研究、在病例-对照研究中的对照如何设定、偏倚如何避免、筛查试验和在筛查过程中的似然比,等等。第2版对原有的16章进行了修订,并增加了全新的6章,新章节均为临床研究中非常重要的主题。本书旨在为临床医生提供评估医学文献的实用工具,为临床研究者夯实研究方法学基础,提升其研究质量,是医学生、临床研究生、各级临床医生和临床研究者,以及一切对临床研究感兴趣的读者开启科研道路的引领性著作。
绪论第1章 临床研究概述:着陆点
观察性研究第2章 描述性研究:可以做什么,不能做什么第3章 观察性研究的偏倚和因果关联第4章 队列研究:迈向结局第5章 病例-对照研究:反方向的研究第6章 与什么作比较?寻找病例-对照研究中的对照第7章 流行病学观察性研究的局限性
筛查试验第8章 筛查试验的应用与滥用第9章 应用似然比优化临床诊断
随机对照试验第10章 提升随机试验中的受试者招募第11章 随机试验样本量的计算:强制性和神秘性第12章 随机试验中分配序列的生成:是机遇,不是选择第13章 非双盲随机试验中分配序列的生成:防止猜测第14章 随机试验中的分配隐藏:对抗破译第15章 随机试验中的剔除和失访:受试者的保留第16章 随机试验中的盲法:盲法的对象及作用第17章 盲法在随机试验中的应用第18章 替代终点和复合终点:到达未知目的地的捷径第19章 随机试验中的多重性Ⅰ:终点及治疗第20章 随机试验中的多重性Ⅱ:亚组分析和期中分析第21章 正在进行的随机临床试验作为前瞻性meta分析的一部分
出版第22章 在医学期刊上发表研究成果:CONSORT声明和其他报告指南
索引
我将《临床研究基本概念》这本书包含在我个人的藏书中,不仅因为Ken和David是我的老师,还因为我看到了他们直接启发了年轻一代的临床科学家。现在,让你自己也受到启发吧!Richard Horton 《柳叶刀》主编
本书是一本简洁、实用的参考书,提出了建设性的方法学建议,以及应当遵循的基本原则,正符合临床医生和临床研究者批判性地阅读文献和科学设计临床研究的需求。作者在每个章节都加入了80年来与他们的研究经验密切相关的深刻见解,将对国人的临床研究实践有重要的指导意义,希望读者能从中受益。王吉耀复旦大学循证医学中心主任复旦大学附属中山医院终身荣誉教授
好书传授方法,更好的书启迪思想。《临床研究基本概念》*的特点之一是作者对临床研究方法背后理论的深刻理解和感悟,他们不但告诉读者做什么、怎么做,更告诉读者为什么这么做。“为什么”是启迪人类智慧*重要的三个字。只有理解了背后的为什么,临床科研才能做得自信,做得灵活,才能因地制宜,才能大胆改革和创造。唐金陵香港中文大学医学院流行病学荣休教授广州市妇女儿童医疗中心临床研究总监
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